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NIRS Infravermelho Próximo - Cortical vascular response to neuroactivation
Phsiological Relevance Advantages Complementary Modalities Early disease detection Monitoring of neoadjuvent chemotherapy Disease confirmation Tumor angiogenesis alters functional response of vascular bed Growing tumors exhibit oxygen s upply/demand imbalance Sensitivity to early disease processes Non-ionizing radiation/non-invasive Not restricted by dense breast or prostethics Sensitivity to early disease processes Comfort
X-Ray Mammography Ultrasound MRI Thermography
Brain Imaging Specific Applications Phsiological Relevance Advantages Complementary Modalities Study of motor sensory functions Cognitive neuroscience Learning/attention disorders Pharmaceutical applications Drug dependency Psychiatric disorders Epilepsy Stroke Trauma/Intensive Care Senile dementia Parkinson's disease
Cortical vascular response to neuroactivation Non-invasive, real-time High temporal resolution High sensitivity to hemodynamics Long term monitoring feasible fMRI/BOLD EEG MEG PET/SPECT
Imaging of the Peripheral Vasculature Specific Applications Phsiological Relevance Advantages Complementary Modalities Assessment of response to vasoactive agents Early disease detection and monitoring (e.g. diabetes) Intensive Care/Resuscitation Sports medicine Standardized assessment of health states Aging
Microvascular function is often affected early in disease processes Fitness measures correlate to the functional state of the microvasculature Disease affects autonomic regulation Non-invasive Sensitive to microvascular hemodynamics Photoplethysmography Electromyography Dynamometry, ergometry Doppler flow measurements
Small Animal Imaging Specific Applications Phsiological Relevance Advantages Complementary Modalities Drug delivery General physiology Reporter gene studies Pain research Functional characterization of animal models Whole body image of small animals feasible Non-invasive Non-ionizing Provides for longitudinal investigations
Micro PET Micro MRI Micro CT Bioluminescence Fluorescence |
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